Family-based association tests using genotype data with uncertainty
نویسندگان
چکیده
منابع مشابه
Family-based association tests using genotype data with uncertainty.
Family-based association studies have been widely used to identify association between diseases and genetic markers. It is known that genotyping uncertainty is inherent in both directly genotyped or sequenced DNA variations and imputed data in silico. The uncertainty can lead to genotyping errors and missingness and can negatively impact the power and Type I error rates of family-based associat...
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ژورنال
عنوان ژورنال: Biostatistics
سال: 2011
ISSN: 1465-4644,1468-4357
DOI: 10.1093/biostatistics/kxr045